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I had a similar experience tuning Squid in this regard.
This setting controls how many connections ATS can make outbound to various Internet servers,
on a per-server basis. The default allows for unlimited connections, and while that may be
useful on a heavily loaded server I find that it actually slows things down a bit.

I decided to go with 48 32 connections per origin server simultaneously.

CONFIG proxy.config.http.origin_max_connections 4832

HTTP RAM Cache

While the default ATS options for this may be optimal under heavy load,
I found using the simpler LRU algorithm much faster and more useful.

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