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• create by default a temporary inbound queue
• set the JMSReplyTo destination on the request message
• set the JMSCorrelationID on the request message
• send the request message
• consume the response and associate the inbound message to the request using the JMSCorrelationID (as you may be performing many concurrent request/responses).

Explicitly specifying InOut

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jms:MyQueue?exchangePattern=InOut

NOTE
From Camel 1.5.1 you You can specify the exchange pattern in DSL rule or Spring configuration.

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{snippet:id=example|lang=xml|url=camel/trunk/components/camel-spring/src/test/resources/org/apache/camel/spring/processor/setExchangePattern.xml}